We spent four intense weeks at the Mount Desert Island Biological Laboratory (MDIBL) in Maine, investigating pathomechanisms of glomerular filtration barrier disruption in zebrafish using state of the art approaches with knockdown techniques, miRNA injections, nanoparticle injections, and studying parabiosis. The MDIBL is a multidisciplinary research center that utilizes marine organisms as well as classical laboratory animals like C.elegans, Drosophila and Zebrafish to study aging and regeneration in human diseases. Being able to use their zebrafish facility was an amazing opportunity to learn handling of these animals and the associated research techniques. The time here allowed us to conduct our own experiments and acquire crucial knowledge that will help us to successfully perform these experiments back in Germany and run our own zebrafish facility in Erlangen, starting end of 2019.
Marwin Gröner, Alexandra Ohs, Nina Sopel, Janina Müller-Deile
Mount Desert Island Biological Laboratory 2019
Prof. Dr. Mario Schiffer, Head of the Medical Clinic 4, Universitätskinikum Erlangen, FAU Erlangen, joined the group for a week as visiting scientist at the MDIBL.