Renal Tubular Physiology

Renal Tubular Physiology
Renal Tubular Physiology
Walsh, Stephen
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Stephen Walsh is a specialist in disorders of the renal tubule, electrolyte and acid base disorders. He runs a specialist renal tubular clinic seeing patients from all over the United Kingdom with genetic and acquired tubular disease.
He is interested in epithelial transport of salts and electrolytes and the way in which these processes can cause rare genetic diseases (such as renal tubular acidosis, Gitelman and Barter syndromes and Dent disease) or more common acquired diseases (such as hypertension and kidney stones).
He runs a laboratory investigating the way in which molecular transport proteins are regulated in tubular epithelial cells and the effect this has on acid base and salt homoeostasis. In particular he is interested in the effect of serine threonine kinases on sodium and chloride transport. Laboratory methods used include work with cell and animal models, electrophysiology, proteomic and phosphoproteomic analysis of human and mouse tissue and in vivo human physiological studies.

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Renal Tubular Physiology