The research in the Sandoghdar group aims to advance experimental and theoretical mastery of light-matter interaction at the nanometer scale. To do this, we combine concepts from quantum optics, laser spectroscopy, optical imaging, scanning probe technology and micro-nanofluidics. Currently, our research encompasses two main areas of quantum-nano-optics and nanobiophotonics. In this latter line of work, we apply ultrasensitive fluorescence and scattering measurements to the detection, microscopy, tracking and manipulation of biological nanoparticles such as viruses, proteins and lipids. Here, we are especially interested in diffusion and transport on and through lipid membranes. An important workhorse of our group is interferometric scattering (iSCAT) microscopy, which allows us to circumvent many limitations of single molecule fluorescence microscopy. Another exciting method employs cryogenics for pushing super-resolution microscopy to the angstrom resolution limit.
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